Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | ATF4 | P18848 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29540443 | 0.85 | MRGPRX4 (0.56) | MRGPRX4CHRNB2CHRNA4TRPV4PLAAT3 | |
| SCHEMBL360071 | 0.85 | MRGPRX4 (0.56) | MRGPRX4CHRNB2CHRNA4TRPV4PLAAT3 | |
| SCHEMBL28497166 | 0.84 | MRGPRX4 (0.51) | MRGPRX4CHRNB2CHRNA4TRPV4ATF4 | |
| Trifluoroacetic Acid SCHEMBL31439609 | 0.81 | MRGPRX4 (0.52) | MRGPRX4CHRNB2CHRNA4PLAAT3PLAAT5 | |
| SCHEMBL5261419 | 0.80 | MRGPRX4 (0.47) | MRGPRX4CHRNB2CHRNA4GRM4TRPV4 | |
| SCHEMBL19555321 | 0.79 | PSEN1 (0.51) | MRGPRX4CHRNB2CHRNA4TRPV4ATF4 | |
| SCHEMBL31439603 | 0.79 | PSEN1 (0.51) | MRGPRX4CHRNB2CHRNA4TRPV4ATF4 | |
| SCHEMBL12611856 | 0.76 | ALDH1A1 (0.63) | MRGPRX4GRM4ALDH1A1 | |
| SCHEMBL20974163 | 0.76 | ATF4 (0.60) | MRGPRX4ATF4ALDH1A1 | |
| SCHEMBL2117441 | 0.74 | ALOX15 (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025015167-A2 | ERASTIN KETONE ANALOGS AND USES THEREOF | EXARTA THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |