SCHEMBL2117441

SCHEMBL2117441

O=C(Cl)COc1ccc(OCC(=O)Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.50
MAPT P10636 2/20 0.47
HPGD P15428 1/20 0.47
ALDH1A1 P00352 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.45
FFAR1 O14842 1/20 0.45
MEN1 O00255 1/20 0.44
PTPN7 P35236 1/20 0.44
KMT2A Q03164 1/20 0.44
PTPN12 Q05209 1/20 0.44
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105460 0.91 ATF4 (0.54) MAPTHPGDALDH1A1SMN1; SMN2MEN1
SCHEMBL4745488 0.91 MAPT (0.47) ALOX15MAPT
SCHEMBL9764750 0.89 RXRA (0.47) ALOX15MAPTHPGDALDH1A1
SCHEMBL22192248 0.89 TDP1 (0.48) ALOX15MAPTHPGDALDH1A1SMN1; SMN2
SCHEMBL1619089 0.89 NPC1 (0.53) ALOX15MAPTHPGDALDH1A1SMN1; SMN2
SCHEMBL2717154 0.89 MAPT (0.62) MAPTHPGDALDH1A1MEN1KMT2A
SCHEMBL2721374 0.89 LMNA (0.56) MAPTHPGDALDH1A1SMN1; SMN2MEN1
SCHEMBL2531951 0.89 POLB (0.54) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL4360696 0.89 PLA2G4B (0.44) ALOX15MAPTSMN1; SMN2
SCHEMBL6013 0.88 ALOX15 (0.68) ALOX15MAPTHPGDALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090071903-A1 Composite Semipermeable Membranes, Methods for Production Thereof and Uses Thereof TORAY INDUSTRIES, INC. (JP) 2009-03-19 US claimed
US-8602222-B2 Composite semipermeable membranes, methods for production thereof and uses thereof TORAY INDUSTRIES, INC. (JP) 2013-12-10 US disclosed
US-8399696-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2013-03-19 US disclosed
US-8399696-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2013-03-19 US disclosed
US-8399696-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2013-03-19 US disclosed
US-20120289614-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-11-15 US disclosed
US-20120289614-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-11-15 US disclosed
US-20120289614-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-11-15 US disclosed
US-8232422-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2012-07-31 US disclosed
US-8232422-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2012-07-31 US disclosed
US-20120095114-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-8053591-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2011-11-08 US disclosed
US-8053591-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2011-11-08 US disclosed
US-8053591-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2011-11-08 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed
US-20090071903-A1 Composite Semipermeable Membranes, Methods for Production Thereof and Uses Thereof TORAY INDUSTRIES, INC. (JP) 2009-03-19 US disclosed
US-20090071903-A1 Composite Semipermeable Membranes, Methods for Production Thereof and Uses Thereof TORAY INDUSTRIES, INC. (JP) 2009-03-19 US disclosed
US-20090071903-A1 Composite Semipermeable Membranes, Methods for Production Thereof and Uses Thereof TORAY INDUSTRIES, INC. (JP) 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 ALOX15 468/4885MAPT 603/4885HPGD 2337/4885
US-20120095114-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 ALOX15 468/4885MAPT 603/4885HPGD 2337/4885
US-20120289614-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 ALOX15 468/4885MAPT 603/4885HPGD 2337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.