Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.34 |
| ▸ | AR | P10275 | 4/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146976 | 0.86 | NR3C2 (0.35) | PARP1NR3C2ARLOXLOXL2 | |
| SCHEMBL30741537 | 0.86 | NR3C2 (0.35) | PARP1NR3C2ARLOXLOXL2 | |
| SCHEMBL17000172 | 0.82 | GABRA1 (0.40) | PARP1NR3C2ARLOXLOXL2 | |
| SCHEMBL15911399 | 0.79 | PNMT (0.46) | SLC6A2HTR2AHTR2BSLC6A3 | |
| SCHEMBL25305878 | 0.75 | KDM6B (0.51) | PARP1NR3C2ARKDM4EALDH1A1 | |
| SCHEMBL29183405 | 0.73 | AR (0.33) | PARP1ARLOXLOXL2 | |
| SCHEMBL29183400 | 0.73 | AR (0.33) | PARP1ARLOXLOXL2 | |
| SCHEMBL18674835 | 0.72 | NR3C2 (0.34) | NR3C2ALOX12KDM4EALOX5 | |
| SCHEMBL648113 | 0.71 | — | — | |
| SCHEMBL1166951 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812105-B | Aminopyridyloxy pyrazole derivative, and preparation method and application thereof | 苏州阿尔脉生物科技有限公司 | 2025-04-01 | — | — | CN | disclosed |