Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29183405 | 1.00 | AR (0.33) | ARPARP1LOXLOXL2 | |
| SCHEMBL17000172 | 0.79 | GABRA1 (0.40) | ARPARP1LOXLOXL2 | |
| SCHEMBL31658872 | 0.77 | APLNR (0.34) | ARPARP1LOXLOXL2 | |
| SCHEMBL5146976 | 0.76 | NR3C2 (0.35) | ARPARP1LOXLOXL2 | |
| SCHEMBL30741537 | 0.76 | NR3C2 (0.35) | ARPARP1LOXLOXL2 | |
| SCHEMBL15911399 | 0.76 | PNMT (0.46) | — | |
| SCHEMBL31440248 | 0.73 | PARP1 (0.36) | ARPARP1LOXLOXL2 | |
| SCHEMBL14706743 | 0.73 | AR (0.42) | ARPARP1LOXLOXL2 | |
| SCHEMBL29183418 | 0.73 | AR (0.36) | ARPARP1LOXLOXL2 | |
| SCHEMBL29183404 | 0.71 | AR (0.32) | ARPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659020-A | Imidazo [1,2-b ] pyridazine derivative, and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-117659043-A | Macrocyclic imidazo [1,2-b ] pyridazine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-03-08 | — | — | CN | disclosed |