SCHEMBL3144029

SCHEMBL3144029

O=C(O)c1ccc(-c2ccc(C(=O)Oc3ccccc3)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.59
PARP10 Q53GL7 1/20 0.58
PRSS1 P07477 1/20 0.56
ACR P10323 1/20 0.56
TMPRSS15 P98073 1/20 0.56
MAPT P10636 4/20 0.54
TDP1 Q9NUW8 2/20 0.54
NSD2 O96028 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PKM P14618 2/20 0.52
SRD5A2 P31213 1/20 0.52
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
EGFR P00533 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9189715 0.94 HSD17B10 (0.62) HSD17B10PARP10PRSS1ACRTMPRSS15
SCHEMBL9696360 0.94 PARP10 (0.66) HSD17B10PARP10MAPTTDP1SMN1; SMN2
SCHEMBL23202513 0.94 PARP10 (0.66) HSD17B10PARP10MAPTTDP1SMN1; SMN2
SCHEMBL817796 0.94 PARP10 (0.63) HSD17B10PARP10PRSS1ACRTMPRSS15
SCHEMBL13019485 0.94 PARP10 (0.63) HSD17B10PARP10PRSS1ACRTMPRSS15
SCHEMBL68278 0.94 PARP10 (0.63) HSD17B10PARP10PRSS1ACRTMPRSS15
Terephthalic Acid SCHEMBL28437942 0.94 PARP10 (0.63) HSD17B10PARP10PRSS1ACRTMPRSS15
Biphenyl SCHEMBL9780962 0.92 MAPT (0.58) HSD17B10PARP10PRSS1ACRTMPRSS15
SCHEMBL2462824 0.92 PARP10 (0.61) PARP10PRSS1ACRTMPRSS15MAPT
SCHEMBL9726251 0.92 PARP10 (0.61) HSD17B10PARP10PRSS1ACRTMPRSS15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100041860-A1 POLYIMIDE, DIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041860-A1 POLYIMIDE, DIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME DDC, AOC1, DDT HSD17B10 2426/4885PARP10 347/4885PRSS1 4140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.