Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444516 | 0.91 | NR1H4 (0.43) | NR1H4BACE1FFAR2HSP90AA1HSP90AB1 | |
| SCHEMBL31444342 | 0.85 | RORC (0.43) | RORCNR1H4PDE5AFFAR2HSP90AA1 | |
| SCHEMBL31444351 | 0.82 | NR1H4 (0.41) | NR1H4FFAR2HSP90AA1HSP90AB1USP30 | |
| SCHEMBL31443722 | 0.80 | NR1H4 (0.34) | NR1H4F10USP30 | |
| SCHEMBL31444288 | 0.80 | NR1H4 (0.43) | NR1H4FFAR2HSP90AA1HSP90AB1USP30 | |
| SCHEMBL31444372 | 0.75 | RORC (0.41) | RORCNR1H4PDE5AFFAR2HSP90AA1 | |
| SCHEMBL31444350 | 0.73 | RORC (0.40) | RORCNR1H4PDE5AFFAR2HSP90AA1 | |
| SCHEMBL31444719 | 0.73 | RORC (0.42) | RORCNR1H4PDE5AFFAR2HSP90AA1 | |
| SCHEMBL31444401 | 0.70 | NR1H4 (0.39) | RORCNR1H4PDE5AHSP90AA1HSP90AB1 | |
| SCHEMBL31444309 | 0.69 | ALDH1A1 (0.40) | PDE5AFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |