Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444288 | 0.87 | NR1H4 (0.43) | NR1H4HSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL31444366 | 0.85 | RORC (0.40) | RORCNR1H4HSP90AA1HSP90AB1PDE5A | |
| SCHEMBL31444372 | 0.78 | RORC (0.41) | RORCNR1H4HSP90AA1HSP90AB1PDE5A | |
| SCHEMBL31444719 | 0.77 | RORC (0.42) | RORCNR1H4HSP90AA1HSP90AB1PDE5A | |
| SCHEMBL31444350 | 0.77 | RORC (0.40) | RORCNR1H4HSP90AA1HSP90AB1PDE5A | |
| SCHEMBL31444516 | 0.76 | NR1H4 (0.43) | NR1H4HSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL31444351 | 0.74 | NR1H4 (0.41) | NR1H4HSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL31444261 | 0.73 | ALDH1A1 (0.43) | PDE5AMEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL27139334 | 0.70 | RIPK1 (0.44) | HSP90AA1HSP90AB1PDE5AMEN1KMT2A | |
| SCHEMBL30525392 | 0.70 | ALDH1A1 (0.41) | RORCMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |