Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444401 | 0.88 | NR1H4 (0.39) | RORCHSP90AA1HSP90AB1PDE5ANR1H4 | |
| SCHEMBL31444719 | 0.79 | RORC (0.42) | RORCHSP90AA1HSP90AB1PDE5ANR1H4 | |
| SCHEMBL31444350 | 0.79 | RORC (0.40) | RORCHSP90AA1HSP90AB1PDE5ANR1H4 | |
| SCHEMBL31443526 | 0.78 | SCN9A (0.34) | RORCHSP90AA1HSP90AB1NR1H4 | |
| SCHEMBL31444342 | 0.78 | RORC (0.43) | RORCHSP90AA1HSP90AB1PDE5ANR1H4 | |
| SCHEMBL31444366 | 0.75 | RORC (0.40) | RORCHSP90AA1HSP90AB1PDE5ANR1H4 | |
| SCHEMBL31444319 | 0.70 | HPGD (0.39) | RORCHSP90AA1PDE5ARIPK1 | |
| SCHEMBL31444405 | 0.68 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1FFAR2 | |
| SCHEMBL31444410 | 0.68 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1FFAR2 | |
| SCHEMBL31444460 | 0.66 | PDE5A (0.56) | HSP90AA1HSP90AB1PDE5AFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |