Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.34 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329807 | 0.83 | MAPK8 (0.52) | MAPK8SIGMAR1ALDH1A1ANO1LCK | |
| SCHEMBL15289490 | 0.81 | CYP3A4 (0.38) | MAPK8ALDH1A1PRKCI | |
| SCHEMBL23713473 | 0.80 | GAA (0.44) | ALDH1A1KDM4EHSP90AB1LMNA | |
| SCHEMBL5164405 | 0.79 | GAA (0.38) | ALDH1A1ANO1KDM4EPRKCIHSP90AB1 | |
| SCHEMBL2788693 | 0.79 | HPGD (0.42) | MAPK8ALDH1A1AKR1B1KDM4E | |
| SCHEMBL27842789 | 0.79 | PKM (0.44) | ALDH1A1PRKCI | |
| SCHEMBL21996057 | 0.78 | TSHR (0.41) | AKR1B1KDM4ERAB9AERCC1ERCC4 | |
| SCHEMBL30799593 | 0.78 | TSHR (0.41) | AKR1B1KDM4ERAB9AERCC1ERCC4 | |
| SCHEMBL10061641 | 0.77 | NOS1 (0.44) | ADRA2BPRKCI | |
| SCHEMBL1578861 | 0.76 | GPR119 (0.44) | MAPK8ANO1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096710-A1 | MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | WO | disclosed |