Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.36 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.36 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18501252 | 0.80 | ALOX5AP (0.35) | PIK3CAGPBAR1POLQSSTR4SQOR | |
| SCHEMBL15204584 | 0.78 | AGBL2 (0.38) | GPBAR1AGBL2AKR1C3AKR1C2PTGER4 | |
| SCHEMBL31445203 | 0.78 | AGBL2 (0.38) | GPBAR1AGBL2AKR1C3AKR1C2PTGER4 | |
| SCHEMBL30082715 | 0.73 | POLB (0.42) | GPBAR1AGBL2PTGER4POLQHCAR2 | |
| SCHEMBL1881949 | 0.73 | POLB (0.42) | GPBAR1AGBL2PTGER4POLQHCAR2 | |
| SCHEMBL38655455 | 0.72 | NNMT (0.40) | AKR1C3AKR1C2SLC22A12 | |
| SCHEMBL31445827 | 0.71 | NR3C2 (0.49) | — | |
| SCHEMBL31444773 | 0.70 | AGBL2 (0.40) | AGBL2AKR1C3AKR1C2PTGER4SSTR4 | |
| SCHEMBL2589049 | 0.70 | POLQ (0.39) | GPBAR1AGBL2PTGER4POLQMAP3K5 | |
| SCHEMBL16703963 | 0.70 | POLQ (0.42) | PIK3CAGPBAR1AGBL2POLQSSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |