Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38656465 | 0.86 | PLCG1 (0.40) | NNMTMEN1KMT2ASIRT6MAPT | |
| SCHEMBL21718906 | 0.80 | ALOX5AP (0.39) | NNMTMEN1KMT2AMAPTSLC22A12 | |
| SCHEMBL25583848 | 0.78 | NNMT (0.40) | NNMTMEN1KMT2ASIRT6MAPT | |
| SCHEMBL29002114 | 0.77 | MEN1 (0.41) | NNMTMEN1KMT2ASIRT6MAPT | |
| SCHEMBL28134501 | 0.73 | NNMT (0.51) | NNMTMEN1KMT2ASIRT6MAPT | |
| SCHEMBL38656591 | 0.73 | CYP11B2 (0.34) | NNMTMEN1KMT2AMAPTERN1 | |
| SCHEMBL31444848 | 0.72 | PIK3CA (0.37) | AKR1C3AKR1C2SLC22A12 | |
| SCHEMBL31207282 | 0.72 | NNMT (0.37) | NNMTMEN1KMT2ASIRT6MAPT | |
| SCHEMBL19469679 | 0.71 | AKR1C3 (0.50) | AKR1C3AKR1C2KDM4E | |
| SCHEMBL31119058 | 0.70 | KDM4E (0.58) | NNMTMEN1KMT2ASIRT6FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026099466-A1 | TARGETED PROTEIN DEGRADATION | MONTE ROSA THERAPEUTICS AG (CH) | 2026-05-15 | — | — | WO | disclosed |