Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31445985 | 0.82 | LMNA (0.43) | LMNATDP1ALDH1A1GAATP53 | |
| SCHEMBL5730708 | 0.80 | LMNA (0.45) | LMNATDP1RECQLGAAPADI1 | |
| SCHEMBL6502285 | 0.79 | PADI1 (0.45) | LMNATDP1RECQLGAAPADI1 | |
| SCHEMBL1953634 | 0.77 | LMNA (0.50) | LMNATDP1RECQLALDH1A1L3MBTL1 | |
| SCHEMBL1953631 | 0.77 | LMNA (0.50) | LMNATDP1RECQLALDH1A1L3MBTL1 | |
| SCHEMBL31444964 | 0.75 | LMNA (0.41) | LMNATDP1TSHRALDH1A1L3MBTL1 | |
| SCHEMBL31447108 | 0.75 | LMNA (0.41) | LMNATDP1ALDH1A1L3MBTL1GAA | |
| SCHEMBL17034773 | 0.74 | SMN1; SMN2 (0.44) | LMNATSHRRECQLGAAMEN1 | |
| SCHEMBL31445677 | 0.70 | SMN1; SMN2 (0.45) | LMNATDP1ALDH1A1GAATP53 | |
| SCHEMBL15715056 | 0.70 | IRAK4 (0.38) | LMNATSHRALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |