SCHEMBL31445985 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	LMNA	P02545	1/20	0.43

▸	TDP1	Q9NUW8	1/20	0.43

▸	ITGAV	P06756	1/20	0.40

▸	ITGB6	P18564	1/20	0.40

▸	CASP3	P42574	1/20	0.40

▸	USP30	Q70CQ3	1/20	0.39

▸	GAA	P10253	1/20	0.38

▸	TP53	P04637	1/20	0.38

▸	DGAT1	O75907	1/20	0.37

▸	CCR5	P51681	1/20	0.37

▸	CTSS	P25774	1/20	0.37

▸	CTSK	P43235	1/20	0.37

▸	ALDH1A1	P00352	1/20	0.36

▸	SMN1; SMN2	Q16637	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31444964	0.86	LMNA (0.41)	LMNATDP1GAATP53CTSS
SCHEMBL31447108	0.86	LMNA (0.41)	LMNATDP1GAATP53CTSS
SCHEMBL1953631	0.85	LMNA (0.50)	LMNATDP1GAATP53ALDH1A1
SCHEMBL1953634	0.85	LMNA (0.50)	LMNATDP1GAATP53ALDH1A1
SCHEMBL31445262	0.82	LMNA (0.37)	LMNATDP1GAATP53ALDH1A1
SCHEMBL5730708	0.82	LMNA (0.45)	LMNATDP1GAASMN1; SMN2
SCHEMBL6502285	0.80	PADI1 (0.45)	LMNATDP1GAASMN1; SMN2
SCHEMBL31446743	0.79	CCR5 (0.37)	CCR5ALDH1A1
SCHEMBL27410245	0.78	SMN1; SMN2 (0.50)	LMNAGAADGAT1CCR5SMN1; SMN2
SCHEMBL31445677	0.78	SMN1; SMN2 (0.45)	LMNATDP1ITGAVITGB6USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025072539-A1	AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF	PLIANT THERAPEUTICS, INC. (US)	2025-04-03	—	—	WO	disclosed