Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1953634 | 0.88 | LMNA (0.50) | LMNATDP1GAATP53ALDH1A1 | |
| SCHEMBL1953631 | 0.88 | LMNA (0.50) | LMNATDP1GAATP53ALDH1A1 | |
| SCHEMBL5730708 | 0.84 | LMNA (0.45) | SMN1; SMN2LMNATDP1GAA | |
| SCHEMBL6502285 | 0.83 | PADI1 (0.45) | SMN1; SMN2LMNATDP1GAA | |
| SCHEMBL18714404 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2LMNAGAAALDH1A1 | |
| SCHEMBL31447108 | 0.79 | LMNA (0.41) | SMN1; SMN2LMNATDP1CTSSGAA | |
| SCHEMBL31444964 | 0.79 | LMNA (0.41) | SMN1; SMN2LMNATDP1CTSSGAA | |
| SCHEMBL31445985 | 0.78 | LMNA (0.43) | SMN1; SMN2LMNATDP1CTSSGAA | |
| SCHEMBL31445968 | 0.78 | TNKS2 (0.36) | SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL12448285 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNACTSLCTSSGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |