Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30630653 | 0.83 | L3MBTL1 (0.41) | RAB9ANPC1MAPTLMNAALDH1A1 | |
| SCHEMBL7131013 | 0.83 | L3MBTL1 (0.41) | RAB9ANPC1MAPTLMNAALDH1A1 | |
| SCHEMBL20241630 | 0.81 | AKR1C3 (0.40) | RAB9ANPC1P2RX7KDM4EALDH1A1 | |
| SCHEMBL31446101 | 0.81 | AKR1C3 (0.39) | RAB9ANPC1P2RX7AKR1C3AKR1C2 | |
| SCHEMBL31446066 | 0.74 | KMT2A (0.37) | P2RX7LMNAALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL31446426 | 0.73 | PDE4A (0.32) | AKR1C3AKR1C2APPCYP3A4CYP2C9 | |
| SCHEMBL31759402 | 0.72 | SPR (0.42) | LMNAAKR1C3AKR1C2APPCYP3A4 | |
| SCHEMBL21585398 | 0.72 | RAB9A (0.36) | RAB9ANPC1MAPTLMNAAKR1C3 | |
| SCHEMBL14973733 | 0.71 | AKR1C3 (0.43) | AKR1C3AKR1C2APPCYP3A4CYP2C9 | |
| SCHEMBL14920534 | 0.70 | PLAU (0.44) | RAB9ANPC1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |