SCHEMBL31447872

SCHEMBL31447872

O=C1CCN(c2cccc(C(=O)N3CCC(CN4CCNCC4)CC3)c2)C(=O)N1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 5/20 0.45
▸ CRBN Q96SW2 5/20 0.45
▸ ALDH1A1 P00352 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ PARP1 P09874 1/20 0.39
▸ SIGMAR1 Q99720 1/20 0.38
▸ HCRTR1 O43613 1/20 0.38
▸ DRD2 P14416 1/20 0.38
▸ CXCR3 P49682 1/20 0.38
▸ LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23134720 0.89 DDB1 (0.44) DDB1CRBNALDH1A1TSHRPARP1
SCHEMBL25935493 0.87 DDB1 (0.46) DDB1CRBNALDH1A1TSHRPARP1
SCHEMBL25935495 0.86 DDB1 (0.56) DDB1CRBNALDH1A1TSHRPARP1
SCHEMBL30501247 0.84 DDB1 (0.41) DDB1CRBNALDH1A1TSHRPARP1
SCHEMBL31447691 0.83 DDB1 (0.53) DDB1CRBNSIGMAR1DRD2
SCHEMBL29013153 0.83 DDB1 (0.43) DDB1CRBNALDH1A1TSHRPARP1
SCHEMBL24671840 0.83 HSD11B1 (0.39) PARP1SIGMAR1DRD2
SCHEMBL23121762 0.83 MGLL (0.38) TSHR
SCHEMBL30066376 0.83 HSD11B1 (0.39) PARP1SIGMAR1DRD2
SCHEMBL30009715 0.83 MGLL (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF BTK, LYN, SYK DDB1 1245/4885CRBN 324/4885ALDH1A1 4704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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