Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23121762 | 1.00 | MGLL (0.38) | MGLLHSD11B1CCR3TSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL23121946 | 0.99 | MGLL (0.37) | MGLLHSD11B1CCR3TSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL30009282 | 0.99 | MGLL (0.37) | MGLLHSD11B1CCR3TSHRNPSR1 | |
| SCHEMBL27123617 | 0.92 | SOS1 (0.40) | MGLL | |
| SCHEMBL28783591 | 0.90 | CCR3 (0.38) | MGLLHSD11B1CCR3TSHRHRH1 | |
| SCHEMBL23134613 | 0.90 | TSHR (0.40) | MGLLHSD11B1TSHRNPSR1KCNH2 | |
| SCHEMBL31677169 | 0.89 | HRH3 (0.38) | MGLLHSD11B1CCR3LIPG | |
| SCHEMBL24671840 | 0.89 | HSD11B1 (0.39) | MGLLHSD11B1 | |
| SCHEMBL30066376 | 0.89 | HSD11B1 (0.39) | MGLLHSD11B1 | |
| SCHEMBL31255494 | 0.89 | TPSAB1 (0.42) | MGLLHSD11B1CCR3TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041724-A1 | BRD9 BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | Novartis AG (CH) | 2022-08-17 | — | — | EP | disclosed |