Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.41 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.38 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144799 | 1.00 | PIK3CA (0.41) | PIK3CANPFFR1NPFFR2PSMB8PSMB5 | |
| SCHEMBL3146146 | 0.90 | CTSL (0.44) | PIK3CAPSMB8PSMB5NFKB1NFKB2 | |
| SCHEMBL3146114 | 0.90 | CTSL (0.44) | PIK3CAPSMB8PSMB5NFKB1NFKB2 | |
| SCHEMBL3149826 | 0.87 | ALDH1A1 (0.41) | PIK3CAPSMB8PSMB5NFKB1NFKB2 | |
| SCHEMBL3149873 | 0.87 | ALDH1A1 (0.41) | PIK3CAPSMB8PSMB5NFKB1NFKB2 | |
| SCHEMBL1432829 | 0.87 | NAMPT (0.45) | PIK3CAPSMB8PSMB5NFKB1NFKB2 | |
| SCHEMBL1432832 | 0.87 | NAMPT (0.45) | PIK3CAPSMB8PSMB5NFKB1NFKB2 | |
| SCHEMBL3153536 | 0.86 | F2R (0.41) | PIK3CAPSMB8PSMB5NFKB1NFKB2 | |
| SCHEMBL3153513 | 0.86 | F2R (0.41) | PIK3CAPSMB8PSMB5NFKB1NFKB2 | |
| SCHEMBL3148190 | 0.86 | HRH3 (0.41) | HRH3KLKB1NAMPTFURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | VANTIA LIMITED (GB) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | CHRM1, ARG1, ARG2 | PIK3CA 3830/4885NPFFR1 695/4885NPFFR2 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.