Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691925 | 0.86 | TSHR (0.50) | OXER1GABRA1GABRB2CMA1NOTUM | |
| SCHEMBL27550174 | 0.84 | OXER1 (0.51) | OXER1GABRA1GABRB2CMA1NOTUM | |
| SCHEMBL4048565 | 0.83 | OXER1 (0.44) | OXER1CMA1NOTUMTSHRRAB9A | |
| SCHEMBL31450569 | 0.79 | LMNA (0.34) | OXER1GABRA1GABRB2TSHRHTR2A | |
| SCHEMBL31450329 | 0.76 | GABRA1 (0.43) | GABRA1GABRB2NOTUMNTSR1CTNNB1 | |
| SCHEMBL4048895 | 0.74 | NOTUM (0.42) | OXER1NOTUMTSHRRAB9AL3MBTL1 | |
| SCHEMBL31450290 | 0.74 | OXER1 (0.45) | OXER1CMA1NOTUMTSHRRAB9A | |
| SCHEMBL18970239 | 0.73 | GABRA1 (0.43) | GABRA1GABRB2NTSR1HTR2ACYP1A2 | |
| SCHEMBL30405639 | 0.72 | RAB9A (0.41) | OXER1NOTUMTSHRRAB9AL3MBTL1 | |
| SCHEMBL1692283 | 0.72 | APP (0.47) | GABRA1GABRB2NOTUMHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-B1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA INC (US) | 2025-02-26 | — | — | EP | claimed |