Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.42 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31451227 | 0.83 | BRD4 (0.42) | L3MBTL1BRD4PIK3CGMEN1KMT2A | |
| SCHEMBL31451355 | 0.77 | POLB (0.44) | KDM4EALDH1A1TSHR | |
| SCHEMBL16896871 | 0.75 | L3MBTL1 (0.52) | L3MBTL1PIK3CGMEN1KMT2AKDM4E | |
| SCHEMBL31451578 | 0.75 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL19030483 | 0.74 | BRD4 (0.57) | L3MBTL1BRD4PIK3CGMEN1KMT2A | |
| SCHEMBL19669656 | 0.74 | ITGB3 (0.54) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18010773 | 0.73 | MAPT (0.46) | L3MBTL1BRD4MEN1KMT2AKDM4E | |
| SCHEMBL31451461 | 0.73 | SLC5A2 (0.40) | L3MBTL1BRD4MEN1KMT2ATSHR | |
| SCHEMBL18581593 | 0.72 | KDM4E (0.54) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL4678275 | 0.71 | HTR6 (0.50) | L3MBTL1PIK3CGPIK3C2APIK3C2BPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054431-A1 | BENZO-FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2025-03-13 | — | — | WO | disclosed |