Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ILK | Q13418 | 5/20 | 0.36 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31451689 | 0.81 | ILK (0.52) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL31451619 | 0.80 | MEN1 (0.34) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL31451683 | 0.80 | APP (0.56) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL31451601 | 0.72 | KDM4E (0.61) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL2314657 | 0.71 | NSD1 (0.64) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL12109842 | 0.71 | ALDH1A1 (0.39) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL31451649 | 0.70 | WDR5 (0.35) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL31451494 | 0.69 | APP (0.56) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL31451616 | 0.69 | GAA (0.47) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL17856111 | 0.69 | ALDH1A1 (0.44) | ALDH1A1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054187-A1 | TGR5 ANTAGONISTS AND METHODS OF USE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2025-03-13 | — | — | WO | disclosed |