Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19117494 | 0.72 | AOC3 (0.49) | KDM4ESCN9APIK3CAAOC3PRKCH | |
| SCHEMBL25310063 | 0.72 | AOC3 (0.44) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21780754 | 0.71 | OPRM1 (0.48) | KDM4ESCN9APIK3CAAOC3PRKCH | |
| SCHEMBL20953955 | 0.70 | KDM4E (0.55) | KDM4ESCN9APIK3CAAOC3PRKCH | |
| SCHEMBL27680973 | 0.70 | RBP4 (0.47) | KDM4E | |
| SCHEMBL15509230 | 0.69 | OPRM1 (0.46) | KDM4ESCN9APIK3CAAOC3PRKCH | |
| SCHEMBL5390961 | 0.69 | KDM4E (0.39) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5448462 | 0.68 | TSHR (0.37) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19105573 | 0.68 | OPRM1 (0.46) | KDM4ESCN9APIK3CAAOC3PRKCH | |
| SCHEMBL19145317 | 0.66 | OPRM1 (0.50) | KDM4ESCN9APIK3CAAOC3PRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016899-A1 | SPIROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2025-01-23 | — | — | WO | disclosed |