Sugi Predict

Sugi Predict / Compounds / SCHEMBL3145225

SCHEMBL3145225

SCHEMBL3145225

CCCCCCCCCCCCCCC(C)C(C)(C)Cl

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 1/20 0.42
▸ SPHK1 Q9NYA1 1/20 0.40
▸ LMNA P02545 1/20 0.39
▸ DNM1 Q05193 2/20 0.39
▸ TSHR P16473 2/20 0.38
▸ THRB P10828 1/20 0.38
▸ ADH1B P00325 1/20 0.38
▸ ADH1C P00326 1/20 0.38
▸ ADH1A P07327 1/20 0.38
▸ ADH4 P08319 1/20 0.38
▸ ADH7 P40394 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ ACE2 Q9BYF1 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ FDPS P14324 3/20 0.35
▸ GPR84 Q9NQS5 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27860264 1.00 OPRM1 (0.42) OPRM1SPHK1LMNADNM1TSHR
Ammonia Solution, Strong SCHEMBL11242043 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR
Ammonia Solution, Strong SCHEMBL5819817 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR
Ammonia Solution, Strong SCHEMBL11217786 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR
Ammonia Solution, Strong SCHEMBL1341496 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR
Ammonia Solution, Strong SCHEMBL1286523 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR
Phosphine SCHEMBL9725351 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR
Ammonia Solution, Strong SCHEMBL2365711 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR
Ammonia Solution, Strong SCHEMBL415492 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR
Ammonia Solution, Strong SCHEMBL4446001 0.98 OPRM1 (0.41) OPRM1SPHK1LMNADNM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104593043-B The method of condensate deodorization SINOPEC CORP. (CN) 2016-05-25 — — CN claimed
CN-102278068-A Method for treating formation water production in gas drilling process — 2011-12-14 — — CN claimed
CN-109678871-A A method of preparing Dibenzylisoquinolinealkaloids compound 山东师范大学 2019-04-26 — — CN disclosed
CN-106220842-B The preparation method of poly glycol monomethyl ether propionic ester 江苏三宝邦佑生物科技有限公司 2018-08-28 — — CN disclosed
CN-108136448-A Removal of coatings from polyethylene terephthalate thermal printing films 吉欧科技聚合物有限责任公司 2018-06-08 — — CN disclosed
CN-108031840-A A kind of heterogeneous nano-superstructure of self-supporting metal and its preparation method and application 国家纳米科学中心 2018-05-15 — — CN disclosed
CN-104777162-B Discoloration instruction device 深圳九星印刷包装集团有限公司 2018-02-09 — — CN disclosed
CN-106366305-A Preparation method for polyethylene glycol methyl ether acetate 江苏三宝邦佑生物科技有限公司 2017-02-01 — — CN disclosed
CN-106220842-A The preparation method of poly glycol monomethyl ether propionic ester 江苏三宝邦佑生物科技有限公司 2016-12-14 — — CN disclosed
CN-104849266-A Conditionally sensitive optically variable film and preparation method thereof SHENZHEN NINE STARS PRINTING & PACKAGING GROUP CO LTD 2015-08-19 — — CN disclosed
CN-204575542-U Look becomes indicating device SHENZHEN NINE STARS PRINTING & PACKAGING GROUP CO LTD 2015-08-19 — — CN disclosed
CN-104777162-A Color change indicating device SHENZHEN NINE STARS PRINTING & PACKAGING GROUP CO LTD 2015-07-15 — — CN disclosed
CN-102278068-B Method for treating formation water production in gas drilling process CHINA PETROLEUM & CHEMICAL 2014-01-15 — — CN disclosed
CN-102278068-A Method for treating formation water production in gas drilling process — 2011-12-14 — — CN disclosed
US-20100074863-A1 ANTI-INFECTIVE PYRROLIDINE DERIVATIVES AND ANALOGS ENANTA PHARMACEUTICALS, INC. 2010-03-25 — — US disclosed
US-20090053175-A1 SUBSTITUTE PYRROLIDINE DERIVATIVES ENANTA PHARMACEUTICALS, INC. 2009-02-26 — — US disclosed
US-20090004140-A1 4-SUBSTITUTED PYRROLIDINE AS ANTI-INFECTIVES ENANTA PHARMACEUTICALS, INC. 2009-01-01 — — US disclosed
WO-2009003009-A1 SUBSTITUTED PYRROLIDINE AS ANTI-INFECTIVES ENANTA PHARMACEUTICALS, INC. (US) 2008-12-31 — — WO disclosed
CN-1121206-C Improved hair conditioning composition COLGATE PALMOLIVE CO (US) 2003-09-17 — — CN disclosed
CN-1232383-A Improved hair conditioning compositions COLGATE PALMOLIVE CO (US) 1999-10-20 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090004140-A1 4-SUBSTITUTED PYRROLIDINE AS ANTI-INFECTIVES EIF2AK2, RNGTT, POLR2E OPRM1 1373/4885SPHK1 1823/4885LMNA 4122/4885
US-20090053175-A1 SUBSTITUTE PYRROLIDINE DERIVATIVES POLRMT, EIF2AK2, NSUN2 OPRM1 1566/4885SPHK1 1691/4885LMNA 3748/4885
US-20100074863-A1 ANTI-INFECTIVE PYRROLIDINE DERIVATIVES AND ANALOGS ZC3HAV1, POLRMT, EIF2AK2 OPRM1 1711/4885SPHK1 1994/4885LMNA 3587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.