Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLL | Q9UGP5 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31452289 | 0.82 | HTR2A (0.35) | HTR2AHTR2CHTR2BL3MBTL1KDM4E | |
| SCHEMBL31452409 | 0.77 | POLL (0.37) | POLLHTR2AHTR2CHTR2BL3MBTL1 | |
| SCHEMBL19249656 | 0.75 | POLL (0.51) | POLLHTR2AHTR2CHTR2BL3MBTL1 | |
| SCHEMBL31452313 | 0.72 | METAP1 (0.36) | KDM4EGAACYP3A4ALDH1A1HSPA1A | |
| SCHEMBL3833035 | 0.72 | POLL (0.51) | POLLHTR2AHTR2CHTR2BL3MBTL1 | |
| SCHEMBL11352016 | 0.67 | KDM4E (0.47) | POLLL3MBTL1KDM4EGAACYP3A4 | |
| SCHEMBL11363652 | 0.66 | CYP1A2 (0.48) | POLLHTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL31452272 | 0.66 | DYRK1A (0.38) | HTR2AHTR2CHTR2BGAAALDH1A1 | |
| SCHEMBL11362493 | 0.66 | POLL (0.42) | POLLHTR2AHTR2CHTR2BL3MBTL1 | |
| SCHEMBL16591167 | 0.63 | HTR2C (0.57) | POLLHTR2AHTR2CHTR2BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066306-A1 | COMPOUNDS FOR TREATING MICROBIAL INFECTIONS, METHODS OF MAKING AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2025-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066306-A1 | COMPOUNDS FOR TREATING MICROBIAL INFECTIONS, METHODS OF MAKING AND USES THEREOF | ATF4, ATF1, CGAS | POLL 4023/4885HTR2A 3864/4885HTR2C 3784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.