Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.35 |
| ▸ | HTR2C | P28335 | 11/20 | 0.35 |
| ▸ | HTR2B | P41595 | 11/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPN | P05981 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31452285 | 0.82 | POLL (0.44) | HTR2AHTR2CHTR2BMAPTHSD17B10 | |
| SCHEMBL31452292 | 0.73 | HTR2A (0.35) | HTR2AHTR2CHTR2BMAOAPOLB | |
| SCHEMBL31452272 | 0.72 | DYRK1A (0.38) | HTR2AHTR2CHTR2BHSD17B10KMT2A | |
| SCHEMBL14732744 | 0.69 | CYP3A4 (0.48) | CYP3A4POLBLMNA | |
| SCHEMBL14732745 | 0.69 | CYP3A4 (0.48) | CYP3A4POLBLMNA | |
| SCHEMBL31452313 | 0.66 | METAP1 (0.36) | MAPTALOX15MEN1USP2KMT2A | |
| SCHEMBL13153860 | 0.65 | PAX8 (0.45) | HSD17B10ALDH1A1CYP3A4KDM4EGAA | |
| SCHEMBL21161386 | 0.62 | PIM1 (0.50) | MAPTALOX15HSD17B10TDP1MEN1 | |
| SCHEMBL30960381 | 0.61 | ALDH1A1 (0.40) | HTR2AHTR2CHTR2BMAPTALOX15 | |
| SCHEMBL4740190 | 0.61 | ALDH1A1 (0.40) | HTR2AHTR2CHTR2BMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066306-A1 | COMPOUNDS FOR TREATING MICROBIAL INFECTIONS, METHODS OF MAKING AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2025-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066306-A1 | COMPOUNDS FOR TREATING MICROBIAL INFECTIONS, METHODS OF MAKING AND USES THEREOF | ATF4, ATF1, CGAS | HTR2A 3864/4885HTR2C 3784/4885HTR2B 4215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.