SCHEMBL31453271

SCHEMBL31453271

NC(=O)N1CCC2CCC2C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.43
F2 P00734 1/20 0.37
PLG P00747 1/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
ST14 Q9Y5Y6 1/20 0.37
CHRNA7 P36544 2/20 0.34
PDE4B Q07343 3/20 0.33
L3MBTL3 Q96JM7 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
CNR2 P34972 4/20 0.33
GAA P10253 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
GPR119 Q8TDV5 1/20 0.32
GNAI3 P08754 2/20 0.32
GNAO1 P09471 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29713762 0.91 HSD11B1 (0.49) HSD11B1F2PLGPRSS1PRSS2
SCHEMBL4743328 0.85 KDM1A (0.37) HSD11B1CHRNA7L3MBTL3GAAGPR119
SCHEMBL29143116 0.79 HSD11B1 (0.44) HSD11B1F2PLGPRSS1PRSS2
SCHEMBL16512369 0.78 ALDH1A1 (0.35) HSD11B1CHRNA7PDE4BGAACHRNB2
SCHEMBL31348284 0.76 HSD11B1 (0.56) HSD11B1F2PLGPRSS1PRSS2
SCHEMBL18493474 0.76 HSD11B1 (0.50) HSD11B1F2PLGPRSS1PRSS2
SCHEMBL4437908 0.76 GNAI3 (0.49) L3MBTL3L3MBTL1GAAGPR119GNAI3
SCHEMBL360381 0.74
SCHEMBL12669587 0.74
SCHEMBL2724587 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4512807-A1 BICYCLOAMINE CARBOXAMIDE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2025-02-26 EP claimed