Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437908 | 0.89 | GNAI3 (0.49) | GAAGNAI3GNAO1GNAI1GPR119 | |
| SCHEMBL4743326 | 0.87 | GNAI3 (0.49) | GNAI3GNAO1GNAI1MBTD1L3MBTL3 | |
| SCHEMBL31453271 | 0.85 | HSD11B1 (0.43) | GAAHSD11B1GNAI3GNAO1GNAI1 | |
| SCHEMBL2377379 | 0.84 | KDM1A (0.35) | KDM1AMAOAMAOBGAAKDM4E | |
| SCHEMBL2566319 | 0.83 | KDM1A (0.37) | KDM1AMAOAMAOBGAAKDM4E | |
| SCHEMBL29713762 | 0.82 | HSD11B1 (0.49) | HSD11B1MBTD1L3MBTL3 | |
| SCHEMBL1517004 | 0.81 | GNAI3 (0.44) | KDM1AMAOAMAOBGAAGNAI3 | |
| SCHEMBL4599189 | 0.81 | DPP4 (0.38) | KDM1AMAOAMAOBGAAGPR119 | |
| Hydrochloric Acid SCHEMBL3286216 | 0.79 | GNAI3 (0.47) | KDM1AMAOAMAOBGAAGNAI3 | |
| Hydrochloric Acid SCHEMBL4120587 | 0.79 | GNAI3 (0.47) | KDM1AMAOAMAOBGAAGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912972-A1 | SUBSTITUTED IMIDAZOLE COMPOUNDS AS KSP INHIBITORS | Novartis AG (CH) | 2008-04-23 | — | — | EP | claimed |
| WO-2007021794-A1 | SUBSTITUTED IMIDAZOLE COMPOUNDS AS KSP INHIBITORS | NOVARTIS AG (CH) | 2007-02-22 | — | — | WO | claimed |