Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16007133 | 0.81 | ALDH1A1 (0.47) | HTTMEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL16056968 | 0.81 | HTT (0.44) | HTTMEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL23692936 | 0.76 | — | — | |
| SCHEMBL20027667 | 0.73 | LPAR1 (0.49) | HTTMEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL16007138 | 0.72 | ALDH1A1 (0.43) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13228930 | 0.70 | HTT (0.62) | HTTMEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL8779255 | 0.69 | SLC6A3 (0.51) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL1775832 | 0.68 | SLC6A3 (0.74) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL12121707 | 0.68 | GABRA1 (0.62) | HTTMEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL19915858 | 0.68 | IDO1 (0.50) | HTTMEN1KMT2AGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119365460-A | Compounds that interact with Ras superfamily proteins for the treatment of cancer, inflammatory diseases, RAS diseases, and fibrotic diseases | 尚医治疗有限责任公司 | 2025-01-24 | — | — | CN | disclosed |