Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 8/20 | 0.43 |
| ▸ | JAK3 | P52333 | 6/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455378 | 0.96 | HPGDS (0.44) | NAMPTJAK2JAK3PTK2HPGDS | |
| SCHEMBL31420375 | 0.95 | NAMPT (0.51) | NAMPTJAK2JAK3PTK2LCK | |
| SCHEMBL31420326 | 0.93 | NAMPT (0.40) | NAMPTJAK2JAK3PTK2HPGDS | |
| SCHEMBL31455683 | 0.85 | JAK2 (0.46) | JAK2JAK3PTK2LCKBTK | |
| SCHEMBL31455264 | 0.84 | USP30 (0.39) | JAK2JAK3HPGDSUSP30GPR119 | |
| SCHEMBL31455205 | 0.82 | PRKCQ (0.38) | JAK2JAK3PTK2USP30JAK1 | |
| SCHEMBL31455277 | 0.81 | PRKCQ (0.37) | NAMPTHPGDSUSP30GPR119TP53 | |
| SCHEMBL30802461 | 0.81 | JAK2 (0.44) | JAK2JAK3 | |
| SCHEMBL27225984 | 0.81 | JAK2 (0.44) | JAK2JAK3 | |
| SCHEMBL31455261 | 0.81 | PTPN2 (0.50) | HPGDSUSP30GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |