Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.39 |
| ▸ | HPGDS | O60760 | 3/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 2/20 | 0.37 |
| ▸ | SKP1 | P63208 | 2/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420326 | 0.89 | NAMPT (0.40) | USP30HPGDSPRKCQJAK3JAK2 | |
| SCHEMBL31455205 | 0.85 | PRKCQ (0.38) | USP30PRKCQJAK3JAK2 | |
| SCHEMBL31455102 | 0.84 | NAMPT (0.45) | USP30HPGDSPRKCQJAK3JAK2 | |
| SCHEMBL31455378 | 0.84 | HPGDS (0.44) | USP30HPGDSPRKCQJAK3JAK2 | |
| SCHEMBL31455261 | 0.83 | PTPN2 (0.50) | USP30HPGDSCKS1BSKP1SKP2 | |
| SCHEMBL31455683 | 0.82 | JAK2 (0.46) | JAK3JAK2 | |
| SCHEMBL31420375 | 0.82 | NAMPT (0.51) | JAK3JAK2GPR119 | |
| SCHEMBL31455277 | 0.80 | PRKCQ (0.37) | USP30HPGDSPRKCQGPR119 | |
| SCHEMBL31420343 | 0.79 | PRMT1 (0.41) | AURKAGSK3AGSK3B | |
| SCHEMBL30802461 | 0.78 | JAK2 (0.44) | CKS1BSKP1SKP2JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |