Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16695250 | 0.87 | LTA4H (0.56) | LTA4HTHRATHRBSMN1; SMN2 | |
| SCHEMBL27438740 | 0.87 | LTA4H (0.67) | LTA4HHTR2AALDH1A1SIGMAR1 | |
| SCHEMBL12156557 | 0.84 | S1PR5 (0.54) | LTA4HHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL7851403 | 0.81 | KDM4E (0.60) | ALDH1A1HTTSMN1; SMN2SIGMAR1 | |
| SCHEMBL4689543 | 0.80 | THRA (0.58) | LTA4HTHRATHRBHTR2AHTR2C | |
| SCHEMBL14205445 | 0.80 | ALDH1A1 (0.64) | LTA4HTHRATHRBHTR2AHTR2C | |
| SCHEMBL6205274 | 0.80 | KDM4E (0.59) | ALDH1A1HTTS1PR5 | |
| SCHEMBL5784653 | 0.80 | KDM4E (0.56) | LTA4HALDH1A1SMN1; SMN2 | |
| SCHEMBL14495108 | 0.79 | HTR2A (0.67) | THRATHRBHTR2AHTR2CHTR7 | |
| SCHEMBL14205446 | 0.79 | LTA4H (0.57) | LTA4HHTR2AGRM2SIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |