SCHEMBL314557

SCHEMBL314557

CCC(C)[CH]c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.41
LMNA P02545 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TRPA1 O75762 1/20 0.36
RELA Q04206 1/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 3/20 0.35
MIF P14174 1/20 0.35
TP53 P04637 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7740381 0.79 TRPA1 (0.42) HTR2ATRPA1ALDH1A1GLATSHR
SCHEMBL6028210 0.79 HTR2A (0.39) HTR2AMEN1KMT2AALDH1A1TSHR
SCHEMBL2332472 0.78 LMNA (0.39) HTR2ALMNAMEN1KMT2ARELA
SCHEMBL16874337 0.77 MEN1 (0.50) HTR2AMEN1KMT2ARELAALDH1A1
SCHEMBL9537809 0.77 CHRNB2 (0.35) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL489023 0.77 MEN1 (0.50) HTR2AMEN1KMT2ARELAALDH1A1
SCHEMBL27460410 0.77 LMNA (0.41) HTR2ALMNAMEN1KMT2AALDH1A1
SCHEMBL555263 0.76 HTR2A (0.48) HTR2AMEN1KMT2ARELAALDH1A1
SCHEMBL28363412 0.76 CYP2C9 (0.43) RELAALDH1A1GAAHPGDL3MBTL1
SCHEMBL9537967 0.76 MEN1 (0.42) HTR2ALMNAMEN1KMT2ATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230072538-A1 METHOD OF MANUFACTURING A SEMICONDUCTOR DEVICE AND PATTERN FORMATION METHOD TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2023-03-09 US claimed
EP-2786985-A2 Antagonists of the glucagon receptor Metabasis Therapeutics, Inc. (US) 2014-10-08 EP claimed
CN-102584829-A Pyrazole and pyrazine diketone derivative and application thereof UNIV SHANDONG 2012-07-18 CN claimed
CN-101367819-B 5-substituent-2-(4-substituted phenyl)-6,7-dihydrogen pyrazole-[1,5-a]pyrazine-4(5H)-ketone derivant and uses thereof UNIV SHANDONG 2010-08-18 CN claimed
CN-101633675-A Preparation and application of 5-substituent group-6-substituent phenyl-2-ferrocenyl pyrazolo [1, 5-a] pyrazine-4(5H)-ketone derivative UNIV SHANDONG 2010-01-27 CN claimed
CN-101367819-A 5-substituent-2-(4-substituted phenyl)-6,7-dihydrogen pyrazole-[1,5-a]pyrazine-4(5H)-ketone derivant and uses thereof UNIV SHANDONG (CN) 2009-02-18 CN claimed
US-6376548-B1 FUNGICIDES; HERBICIDES; INSECTICIDES ROHM AND HAAS COMPANY 2002-04-23 US claimed
EP-0234944-B1 INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-04-10 EP claimed
EP-0234944-A1 Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines ROHM AND HAAS COMPANY (US) 1987-09-02 EP claimed
US-11718758-B2 Aqueous dispersion of colored particles MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2023-08-08 US disclosed
EP-3725854-B1 COLORED PARTICLE AQUEOUS DISPERSION MITSUBISHI PENCIL CO (JP) 2023-07-05 EP disclosed
CN-111465662-B Aqueous dispersion of coloured particles 三菱铅笔株式会社 2023-05-26 CN disclosed
US-20230072538-A1 METHOD OF MANUFACTURING A SEMICONDUCTOR DEVICE AND PATTERN FORMATION METHOD TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2023-03-09 US disclosed
CN-110437046-B Fluorine atom-containing polymer and field of use thereof 日产化学工业株式会社 2022-08-16 CN disclosed
US-5175186-A Inhibits pancreas lepase and useful agent in treatment of obesity, hyperlipemia, atherosclerosis and arteriosclerosis HOFFMANN-LA ROCHE INC. (US) 1992-12-29 US disclosed
US-4963582-A ANTHELMINTICS, ACARICIDES, INSECTICIDES SANKYO COMPANY LIMITED (JP) 1990-10-16 US disclosed
EP-0342710-A1 Macrolide compounds, their preparation and their use Sankyo Company Limited (JP) 1989-11-23 EP disclosed
EP-0246739-A2 Macrolide compounds, their preparation and their use SANKYO COMPANY LIMITED (JP) 1987-11-25 EP disclosed
EP-0138750-B1 PROCESS FOR THE PRODUCTION OF SUBSTITUTED BENZIMIDAZOLES CIBA-GEIGY AG (CH) 1987-09-09 EP disclosed
EP-0138750-A1 Process for the production of substituted benzimidazoles CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed