Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27375376 | 1.00 | MEN1 (0.47) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL31457052 | 0.84 | MAPT (0.52) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL27375399 | 0.84 | MAPT (0.52) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL31457034 | 0.79 | HSD17B10 (0.43) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL27374802 | 0.79 | HSD17B10 (0.43) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL27375343 | 0.78 | MAPT (0.50) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL31456955 | 0.78 | MAPT (0.50) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL31456969 | 0.77 | LOXL2 (0.48) | MEN1KMT2AMAPTSMN1; SMN2MAOB | |
| SCHEMBL7844969 | 0.77 | MTNR1B (0.64) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL27374959 | 0.77 | LOXL2 (0.48) | MEN1KMT2AMAPTSMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |