Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27374959 | 1.00 | LOXL2 (0.48) | LOXL2SOS1KCNH3MAOBTAAR1 | |
| SCHEMBL31457034 | 0.87 | HSD17B10 (0.43) | LOXL2SOS1KCNH3MAOBTAAR1 | |
| SCHEMBL27374802 | 0.87 | HSD17B10 (0.43) | LOXL2SOS1KCNH3MAOBTAAR1 | |
| SCHEMBL27375511 | 0.85 | SOS1 (0.41) | SOS1MAOBTAAR1MEN1EGFR | |
| SCHEMBL31456939 | 0.85 | SOS1 (0.41) | SOS1MAOBTAAR1MEN1EGFR | |
| SCHEMBL31456993 | 0.84 | LOXL2 (0.44) | LOXL2SOS1KCNH3TAAR1IDO1 | |
| SCHEMBL27374825 | 0.84 | LOXL2 (0.44) | LOXL2SOS1KCNH3TAAR1IDO1 | |
| SCHEMBL30751434 | 0.84 | ALDH1A1 (0.40) | SOS1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL31457052 | 0.84 | MAPT (0.52) | SOS1KCNH3MAOBMEN1MAPT | |
| SCHEMBL27374880 | 0.84 | ALDH1A1 (0.40) | SOS1MEN1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |