Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27374825 | 1.00 | LOXL2 (0.44) | LOXL2RAD52SOS1CYP17A1CYP21A2 | |
| SCHEMBL27374959 | 0.84 | LOXL2 (0.48) | LOXL2SOS1KCNH3IDO1JAK2 | |
| SCHEMBL31456969 | 0.84 | LOXL2 (0.48) | LOXL2SOS1KCNH3IDO1JAK2 | |
| SCHEMBL31457034 | 0.83 | HSD17B10 (0.43) | LOXL2SOS1KCNH3KDM4EL3MBTL1 | |
| SCHEMBL27374802 | 0.83 | HSD17B10 (0.43) | LOXL2SOS1KCNH3KDM4EL3MBTL1 | |
| SCHEMBL31457046 | 0.81 | KIF11 (0.46) | LOXL2CYP11B1KDM4EL3MBTL1MEN1 | |
| SCHEMBL27374686 | 0.81 | KIF11 (0.46) | LOXL2CYP11B1KDM4EL3MBTL1MEN1 | |
| SCHEMBL31456939 | 0.81 | SOS1 (0.41) | SOS1FLT1KDRKDM4EL3MBTL1 | |
| SCHEMBL27375511 | 0.81 | SOS1 (0.41) | SOS1FLT1KDRKDM4EL3MBTL1 | |
| SCHEMBL24010924 | 0.77 | RAD52 (0.57) | RAD52SOS1IDO1FLT1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4567035-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Nextgen Bioscience Co., Ltd. (KR) | 2025-06-11 | — | — | EP | disclosed |
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |