Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456939 | 1.00 | SOS1 (0.41) | SOS1TRPV1TAAR1MTORMAOB | |
| SCHEMBL27374959 | 0.85 | LOXL2 (0.48) | SOS1TAAR1MAOBEGFRMEN1 | |
| SCHEMBL31456969 | 0.85 | LOXL2 (0.48) | SOS1TAAR1MAOBEGFRMEN1 | |
| SCHEMBL27374863 | 0.84 | KIF11 (0.48) | TAAR1KIF11KDM4EALDH1A1GAA | |
| SCHEMBL31456953 | 0.84 | KIF11 (0.48) | TAAR1KIF11KDM4EALDH1A1GAA | |
| SCHEMBL31456993 | 0.81 | LOXL2 (0.44) | SOS1TAAR1KDRFLT1KDM4E | |
| SCHEMBL27374825 | 0.81 | LOXL2 (0.44) | SOS1TAAR1KDRFLT1KDM4E | |
| SCHEMBL31457034 | 0.80 | HSD17B10 (0.43) | SOS1TAAR1MAOBKDM4EMEN1 | |
| SCHEMBL27374802 | 0.80 | HSD17B10 (0.43) | SOS1TAAR1MAOBKDM4EMEN1 | |
| SCHEMBL30751434 | 0.77 | ALDH1A1 (0.40) | SOS1CA1CA2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |