Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456957 | 0.74 | ASIC3 (0.49) | TAAR1LOXL2CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL26103203 | 0.73 | CNR2 (0.46) | CNR2TRPV1 | |
| SCHEMBL17588944 | 0.71 | MAP4K4 (0.48) | MAP4K4 | |
| SCHEMBL2039891 | 0.70 | CYP17A1 (0.67) | TAAR1LOXL2CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL24459423 | 0.70 | TAAR1 (0.58) | TAAR1LOXL2CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL31457060 | 0.69 | ADCY10 (0.37) | TAAR1LOXL2MAP4K4 | |
| SCHEMBL30824220 | 0.68 | ADORA2A (0.49) | CNR2 | |
| SCHEMBL20600142 | 0.68 | ADORA2A (0.49) | CNR2 | |
| SCHEMBL27375239 | 0.68 | GRM5 (0.49) | TAAR1LOXL2CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL1083427 | 0.68 | HSP90AA1 (0.45) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |