Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 3/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.35 |
| ▸ | LOX | P28300 | 2/20 | 0.35 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30437053 | 0.74 | ASIC3 (0.66) | ASIC3MAP4K4 | |
| SCHEMBL21055972 | 0.74 | ASIC3 (0.66) | ASIC3MAP4K4 | |
| SCHEMBL31457035 | 0.74 | TAAR1 (0.39) | LOXL2TAAR1CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL2039891 | 0.71 | CYP17A1 (0.67) | LOXL2TAAR1CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL30337333 | 0.71 | ASIC3 (0.79) | ASIC3LOXL2MAP4K4 | |
| SCHEMBL18049349 | 0.70 | LOXL2 (0.62) | LOXL2TAAR1LOXLOXL3 | |
| SCHEMBL314105 | 0.69 | ASIC3 (0.67) | ASIC3 | |
| SCHEMBL14303459 | 0.68 | LOXL2 (0.64) | ASIC3LOXL2CYP17A1CYP11B1LOX | |
| SCHEMBL19072733 | 0.68 | GRM5 (0.41) | ASIC3 | |
| SCHEMBL27675974 | 0.68 | ASIC3 (0.73) | ASIC3LOXL2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |