Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6486540 | 0.86 | KMO (0.36) | KMODGAT1NPC1PTPN1MAPT | |
| SCHEMBL16023365 | 0.82 | NPC1 (0.42) | DGAT1NPC1KDM4E | |
| SCHEMBL21055380 | 0.81 | DGAT1 (0.36) | DGAT1NPC1MAPT | |
| SCHEMBL31460064 | 0.81 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL21055191 | 0.80 | DGAT1 (0.36) | DGAT1NPC1MAPT | |
| SCHEMBL27228071 | 0.79 | CNR2 (0.39) | DGAT1NPC1MAPT | |
| SCHEMBL31588698 | 0.79 | DGAT1 (0.37) | DGAT1NPC1MAPTKDM4E | |
| SCHEMBL5511811 | 0.78 | NPC1 (0.37) | DGAT1NPC1PTPN1MAPT | |
| SCHEMBL29172538 | 0.78 | NPC1 (0.37) | DGAT1NPC1MAPTKDM4E | |
| SCHEMBL22013956 | 0.77 | DGAT1 (0.36) | DGAT1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677749-A | Azaquinazoline pan KRAS inhibitors | 米拉蒂治疗股份有限公司 | 2025-03-21 | — | — | CN | disclosed |