Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29646356 | 0.87 | CTSD (0.62) | HDAC3HDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL22987538 | 0.87 | CTSD (0.62) | HDAC3HDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31461706 | 0.81 | CTSD (0.73) | NPC1RAB9ACTSDALDH1A1LMNA | |
| SCHEMBL23611756 | 0.76 | SMN1; SMN2 (0.55) | HDAC3HDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL24862994 | 0.75 | HPGD (0.52) | HDAC3HDAC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL1655461 | 0.74 | SMN1; SMN2 (0.56) | HDAC3HDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17206370 | 0.72 | SMN1; SMN2 (0.51) | HDAC3HDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1655964 | 0.72 | IRAK4 (0.68) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL11212937 | 0.71 | HTT (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL2104535 | 0.71 | IRAK4 (0.67) | SMN1; SMN2CTSDALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |