Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987538 | 1.00 | CTSD (0.62) | CTSDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL31461674 | 0.87 | HDAC3 (0.53) | CTSDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL28352325 | 0.83 | CTSD (0.62) | CTSDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL2104535 | 0.83 | IRAK4 (0.67) | CTSDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL1655461 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL17206370 | 0.81 | SMN1; SMN2 (0.51) | CTSDSMN1; SMN2ALDH1A1HTTNPC1 | |
| SCHEMBL2301384 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL1655964 | 0.80 | IRAK4 (0.68) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL29930602 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL11212937 | 0.80 | HTT (0.49) | SMN1; SMN2KMT2AALDH1A1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |