Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | HCN1 | O60741 | 1/20 | 0.38 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23623280 | 0.87 | ALOX15 (0.47) | ALOX15HSD17B10KCNK3KCNK9POLB | |
| SCHEMBL23623443 | 0.85 | HPGD (0.45) | HSD17B10KCNK3KCNK9KDM4EPOLB | |
| SCHEMBL31461708 | 0.85 | OPRM1 (0.41) | RXFP1KCNK3KCNK9KDM4EF2R | |
| SCHEMBL31461685 | 0.81 | SMN1; SMN2 (0.41) | KCNK3KCNK9KDM4EOPRM1HCN1 | |
| SCHEMBL23611716 | 0.81 | KCNK3 (0.45) | ALOX15HSD17B10KCNK3KCNK9POLB | |
| SCHEMBL29930594 | 0.81 | KCNK3 (0.45) | ALOX15HSD17B10KCNK3KCNK9POLB | |
| SCHEMBL23623256 | 0.80 | OPRM1 (0.39) | RXFP1KCNK3KCNK9L3MBTL1F2R | |
| SCHEMBL31461662 | 0.80 | RIPK1 (0.44) | RXFP1RIPK1KCNK3KCNK9F2R | |
| SCHEMBL23623581 | 0.80 | POLB (0.47) | ALOX15HSD17B10KCNK3KCNK9POLB | |
| SCHEMBL23623264 | 0.79 | ALOX15 (0.44) | ALOX15HSD17B10KCNK3KCNK9ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |