Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461704 | 0.78 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1MAPTNSD2 | |
| SCHEMBL31461659 | 0.73 | ELANE (0.46) | RAB9ANPC1KMT2AELANE | |
| SCHEMBL26601318 | 0.69 | HDAC3 (0.44) | RAB9ASMN1; SMN2NPC1KMT2ALMNA | |
| SCHEMBL11823531 | 0.67 | ELANE (0.40) | SMN1; SMN2KMT2AELANEALDH1A1KDM4E | |
| SCHEMBL31461687 | 0.66 | HPGD (0.43) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL31461691 | 0.66 | PDE10A (0.44) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL31461688 | 0.66 | PDE10A (0.44) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL31461728 | 0.66 | SMN1; SMN2 (0.43) | RAB9ASMN1; SMN2NPC1MAPTKMT2A | |
| SCHEMBL5765002 | 0.65 | ELANE (0.42) | ELANEALDH1A1KDM4E | |
| SCHEMBL31461674 | 0.65 | HDAC3 (0.53) | RAB9ASMN1; SMN2NPC1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |