Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | UBE2I | P63279 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461728 | 0.86 | SMN1; SMN2 (0.43) | HPGDSMN1; SMN2TP53GLARAB9A | |
| SCHEMBL31461688 | 0.86 | PDE10A (0.44) | HPGDSMN1; SMN2TP53GLARAB9A | |
| SCHEMBL31461691 | 0.86 | PDE10A (0.44) | HPGDSMN1; SMN2TP53GLARAB9A | |
| SCHEMBL31461695 | 0.82 | TP53 (0.41) | HPGDSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL31461675 | 0.78 | RAB9A (0.46) | HPGDSMN1; SMN2TP53GLARAB9A | |
| SCHEMBL31461652 | 0.76 | KDM4E (0.49) | HPGDTP53GLAKDM4EALDH1A1 | |
| SCHEMBL31461742 | 0.71 | RAB9A (0.38) | SMN1; SMN2RAB9ANPC1POLBKDM4E | |
| SCHEMBL31461655 | 0.71 | HPGD (0.48) | HPGDSMN1; SMN2TP53GLARAB9A | |
| SCHEMBL23611755 | 0.71 | ALOX15 (0.47) | HPGDSMN1; SMN2TP53GLARAB9A | |
| SCHEMBL29930729 | 0.71 | ALOX15 (0.47) | HPGDSMN1; SMN2TP53GLARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |