Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 7/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461691 | 1.00 | PDE10A (0.44) | PDE10ASMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL31461687 | 0.86 | HPGD (0.43) | PDE10ASMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL31461728 | 0.86 | SMN1; SMN2 (0.43) | PDE10ASMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL31461695 | 0.81 | TP53 (0.41) | SMN1; SMN2HPGDNPC1RAB9ATP53 | |
| SCHEMBL31461675 | 0.78 | RAB9A (0.46) | SMN1; SMN2HPGDNPC1RAB9APOLB | |
| SCHEMBL31461652 | 0.75 | KDM4E (0.49) | HPGDTP53GLALMNAMAPT | |
| SCHEMBL31461702 | 0.71 | ALDH1A1 (0.41) | HPGDRAB9ATP53GLALMNA | |
| SCHEMBL26629775 | 0.71 | ALDH1A1 (0.41) | HPGDRAB9ATP53GLALMNA | |
| SCHEMBL31461697 | 0.71 | ALDH1A1 (0.41) | HPGDRAB9ATP53GLALMNA | |
| SCHEMBL31461742 | 0.71 | RAB9A (0.38) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |