Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.46 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NEK1 | Q96PY6 | 3/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29082871 | 1.00 | KDM4E (0.46) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL26613987 | 0.85 | XDH (0.56) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL29069192 | 0.81 | JMJD6 (0.47) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1647107 | 0.77 | JMJD6 (0.46) | JMJD6ALDH1A1MAPTXDH | |
| SCHEMBL1646370 | 0.76 | XDH (0.55) | JMJD6XDH | |
| SCHEMBL26613985 | 0.74 | KDM4E (0.51) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL26619457 | 0.74 | JMJD6 (0.45) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1647683 | 0.74 | KMO (0.44) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL30593721 | 0.72 | XDH (0.59) | XDH | |
| SCHEMBL1647090 | 0.72 | XDH (0.59) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250289809-A1 | COMPOUNDS USEFUL FOR GOUT | ATOM BIOSCIENCE AMERICA CORPORATION (US) | 2025-09-18 | — | — | US | disclosed |
| EP-4516788-A1 | COMPOUND CAPABLE OF BEING USED FOR GOUT | Atom Therapeutics Co., Ltd (CN) | 2025-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250289809-A1 | COMPOUNDS USEFUL FOR GOUT | SLC10A1, ABCG2, SLC10A6 | KDM4E 3183/4885KDM6B 2997/4885KDM5C 3191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.