Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645546 | 0.94 | CYP2A6 (0.57) | CYP2A6CYP1A2HSD17B1HSD17B2NQO1 | |
| SCHEMBL2252619 | 0.92 | CYP2A6 (0.50) | CYP2A6CYP1A2HSD17B1HSD17B2NQO1 | |
| SCHEMBL2254126 | 0.92 | CYP2A6 (0.50) | CYP2A6CYP1A2HSD17B1HSD17B2NQO1 | |
| SCHEMBL1121819 | 0.80 | NQO1 (0.48) | CYP1A2NQO1KDM4EMEN1MAPK1 | |
| SCHEMBL6611816 | 0.80 | AGXT (0.34) | CYP2A6CYP1A2KDM4EGSTP1RAB9A | |
| SCHEMBL208820 | 0.79 | CYP1A2 (0.30) | CYP2A6CYP1A2 | |
| SCHEMBL443070 | 0.79 | CYP1A2 (0.79) | CYP2A6CYP1A2HSD17B1HSD17B2NQO1 | |
| SCHEMBL29447161 | 0.79 | CYP1A2 (0.79) | CYP2A6CYP1A2HSD17B1HSD17B2NQO1 | |
| SCHEMBL7197554 | 0.79 | CA12 (0.33) | CYP2A6CYP1A2NQO1 | |
| SCHEMBL3142737 | 0.79 | ALDH1A1 (0.41) | KDM4EPOLBKMT2AAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1693 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184703-A | Synthesis method of alpha-substituted chiral phosphonate compound | 中国人民解放军军事科学院防化研究院 | 2024-06-14 | — | — | CN | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| CN-117486907-A | N 2 O-type BODIPY derivative and preparation method and application thereof | 安徽师范大学 | 2024-02-02 | — | — | CN | claimed |
| CN-117430511-A | Preparation and application of novel cinnamic acid analogue | 广东轻工职业技术学院 | 2024-01-23 | — | — | CN | claimed |
| CN-117143340-A | Preparation method and application of enol-terminated sulfhydryl compound | 益丰新材料股份有限公司 | 2023-12-01 | — | — | CN | claimed |
| WO-2023169615-A1 | DIAMINE COMPOUND WITH FLUORESCENT PROPERTIES, METHOD OF ITS PREPARATION, A POLYIMIDE FILM AND A POLYEPOXIDE CONTAINING THIS DIAMINE | TOSEDA S.R.O. (CZ) | 2023-09-14 | — | — | WO | claimed |
| CN-116621922-A | PROTAC compound for degrading cyclooxygenase 2 and influenza virus nucleoprotein, and preparation method and application thereof | 中国科学院微生物研究所 | 2023-08-22 | — | — | CN | claimed |
| WO-2023107547-A2 | AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | claimed |
| EP-3720858-B1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2023-06-07 | — | — | EP | claimed |
| CN-116199616-A | Modified oxime ester compound, preparation method thereof and photo-curing composition | 常州强力电子新材料股份有限公司 | 2023-06-02 | — | — | CN | claimed |
| US-4055651-A | THROMBOSIS INHIBITORS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-10-25 | — | — | US | claimed |
| US-4055636-A | THROMBOSIS INHIBITORS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-10-25 | — | — | US | claimed |
| US-4046876-A | THROMBIN INHIBITORS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1977-09-06 | — | — | US | claimed |
| US-4041156-A | ANTITHROMBOGENIC AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1977-08-09 | — | — | US | claimed |
| US-4036955-A | TREATMENT OF THROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-07-19 | — | — | US | claimed |
| US-4018915-A | ANTITHROMBOTIC | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-04-19 | — | — | US | claimed |
| US-4018913-A | N2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-04-19 | — | — | US | claimed |
| US-4016196-A | HEATING GLYCIDIC ESTERS | NISSHIN FLOUR MILLING CO., LTD. (JA) | 1977-04-05 | — | — | US | claimed |
| US-3993645-A | Stilbene optical brighteners and compositions brightened therewith | STERLING DRUG INC. (US) | 1976-11-23 | — | — | US | claimed |
| US-3932301-A | NYLON, POLYESTERS | STERLING DRUG INC. (US) | 1976-01-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ADRB3, ADRB1, ADRB2 | CYP2A6 756/4885CYP1A2 633/4885HSD17B1 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.