Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9950334 | 0.81 | GFER (0.36) | SMN1; SMN2ESR2ESR1KMT2AMAPT | |
| SCHEMBL30281198 | 0.81 | GFER (0.36) | SMN1; SMN2ESR2ESR1KMT2AMAPT | |
| SCHEMBL14842706 | 0.73 | ATP4A (0.44) | ALDH1A1SMN1; SMN2HTTLMNAESR2 | |
| SCHEMBL22127662 | 0.73 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2HTTLMNAESR2 | |
| SCHEMBL9957060 | 0.73 | TBXA2R (0.40) | ALDH1A1SMN1; SMN2HTTLMNAESR2 | |
| SCHEMBL9949570 | 0.72 | GABRG2 (0.68) | RAB9AGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16217689 | 0.69 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2HTTLMNAESR2 | |
| SCHEMBL5604475 | 0.68 | ESR2 (0.53) | ALDH1A1SMN1; SMN2HTTLMNAESR2 | |
| SCHEMBL2304799 | 0.68 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2HTTLMNAESR2 | |
| SCHEMBL10910459 | 0.66 | ESR2 (0.68) | ALDH1A1LMNAESR2ESR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068090-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2025-04-03 | — | — | WO | disclosed |