SCHEMBL3146571

SCHEMBL3146571

C[SiH](C)Oc1ccc(N)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.52
MAPK1 P28482 2/20 0.52
ALDH1A1 P00352 7/20 0.50
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
TEAD4 Q15561 1/20 0.46
MAPT P10636 5/20 0.44
POLB P06746 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
MAOA P21397 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
APP P05067 2/20 0.41
NPC1 O15118 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
NR4A1 P22736 1/20 0.41
MAOB P27338 1/20 0.41
MITF O75030 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12585158 0.76 ACHE (0.50) TDP1ALDH1A1CYP3A4TSHRTEAD4
SCHEMBL21295142 0.74 NFE2L2 (0.41) TDP1MAOAAPPNPC1RAB9A
SCHEMBL4454897 0.74 MEN1 (0.50) ALDH1A1CYP3A4MAPTMEN1KMT2A
SCHEMBL22366368 0.74 APP (0.39) CYP3A4APP
SCHEMBL5422997 0.74 LMNA (0.42) TDP1ALDH1A1CYP3A4TSHRMAPT
SCHEMBL3151161 0.73 TDP1 (0.41) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL2354326 0.72 CA4 (0.48) ALDH1A1TSHRMAOAACHE
SCHEMBL5097 0.69
Ethane SCHEMBL6670400 0.69 TDP1 (0.60) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL8526630 0.69 TDP1 (1.00) TDP1MAPK1ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024659-B Preparation method of large-particle-size high-solid-content styrene-butadiene latex 河南大树实业有限公司 2024-05-31 CN claimed
CN-117024659-A Preparation method of large-particle-size high-solid-content styrene-butadiene latex 河南大树实业有限公司 2023-11-10 CN claimed
CN-110835451-A Thermosetting resin composition and application thereof 陕西生益科技有限公司 2020-02-25 CN claimed
CN-110607153-A Sealant for MS double-component hollow glass and preparation method thereof 安徽蓝色经典新材料科技有限公司 2019-12-24 CN claimed
CN-117024659-B Preparation method of large-particle-size high-solid-content styrene-butadiene latex 河南大树实业有限公司 2024-05-31 CN disclosed
CN-117024659-B Preparation method of large-particle-size high-solid-content styrene-butadiene latex 河南大树实业有限公司 2024-05-31 CN disclosed
CN-117551418-B Adhesive for aluminum plastic film and preparation process thereof 江阴苏达汇诚复合材料有限公司 2024-04-02 CN disclosed
CN-117551418-A Adhesive for aluminum plastic film and preparation process thereof 江阴苏达汇诚复合材料有限公司 2024-02-13 CN disclosed
CN-117024659-A Preparation method of large-particle-size high-solid-content styrene-butadiene latex 河南大树实业有限公司 2023-11-10 CN disclosed
CN-117024659-A Preparation method of large-particle-size high-solid-content styrene-butadiene latex 河南大树实业有限公司 2023-11-10 CN disclosed
CN-115991873-A Low-dielectric fluorinated aromatic polyimide film and preparation method thereof 慧创(东莞)材料技术有限责任公司 2023-04-21 CN disclosed
CN-110835451-B Thermosetting resin composition and application thereof 陕西生益科技有限公司 2022-11-29 CN disclosed
CN-110607153-A Sealant for MS double-component hollow glass and preparation method thereof 安徽蓝色经典新材料科技有限公司 2019-12-24 CN disclosed
CN-110607153-A Sealant for MS double-component hollow glass and preparation method thereof 安徽蓝色经典新材料科技有限公司 2019-12-24 CN disclosed
CN-105778509-A Environment-friendly rubber composition and self-lubricating rubber sealing element prepared from same 北京凯瑞捷成新材料科技有限公司 2016-07-20 CN disclosed
EP-1782881-B1 Membrane and associated method GEN ELECTRIC (US) 2010-02-10 EP disclosed
EP-1783147-B1 Composition and associated method GEN ELECTRIC (US) 2009-05-13 EP disclosed
EP-1783147-A1 Composition and associated method GENERAL ELECTRIC COMPANY (US) 2007-05-09 EP disclosed
EP-1782881-A1 Membrane and associated method General Electric Company (US) 2007-05-09 EP disclosed
US-4981946-A Marine paint composition comprising quinone/polyamine polymer ERHAN SEMIH (US) 1991-01-01 US disclosed