Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14828478 | 0.85 | ESR2 (0.61) | MEN1KMT2AESR2ESR1LTA4H | |
| SCHEMBL12585158 | 0.76 | ACHE (0.50) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL21295142 | 0.74 | NFE2L2 (0.41) | NPC1CA1CA2RAB9ACA9 | |
| SCHEMBL5422997 | 0.74 | LMNA (0.42) | MEN1KMT2AKDM4EALDH1A1CA1 | |
| SCHEMBL3146571 | 0.74 | TDP1 (0.52) | MEN1KMT2ANPC1ALDH1A1CYP3A4 | |
| SCHEMBL2354326 | 0.72 | CA4 (0.48) | LTA4HNR1H2BAXALDH1A1CA1 | |
| SCHEMBL6082860 | 0.72 | MAPT (0.35) | KMT2AESR2ESR1KDM4EALDH1A1 | |
| SCHEMBL14828480 | 0.72 | CYP3A4 (0.52) | ESR2ESR1CA12ALDH1A1CA2 | |
| Mequinol SCHEMBL1535640 | 0.69 | ESR2 (0.84) | MEN1KMT2AESR2ESR1LTA4H | |
| Mequinol SCHEMBL166535 | 0.69 | ESR2 (0.84) | MEN1KMT2AESR2ESR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1598402-B1 | CURABLE COMPOSITIONS | KANEKA CORP (JP) | 2012-05-02 | — | — | EP | disclosed |